Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

We can provide high-quality MMAE and its derived impurities.Moreover, we provide the following technical development services:

Reliable and available kilogram-level supply;
kilogram-level GMP supply in commercial production stage;
Complete DMF registration;
CMC and regulatory affair service(IND, NDA) of Drug-Linker based on this product.

Product Specifications:purity≥99%, Total Impurities≤1.0%, KF≤1.0%