• ADC & High Potency API

    From R&D to Commercial Manufacturing — One Stop Service

    ChemExpress is one of the earliest CDMO companies engaged in the production of ADC (Antibody Drug Conjugates) & Highly Potent Active Pharmaceutical Ingredients (HPAPIs or HPAIs). We can provide a one-stop CRO & CDMO service for the small molecule part of ADC drugs, as well as customized ADC conjugation services. We are equipped with R&D laboratories, kilogram-scale GMP laboratories and commercial-scale GMP manufacturing plants for ADC small molecules, which can provide a one-stop service for your project from preclinical to commercialization.

    We have 80+ payload (in stock), 400+ linkers (in stock) and 1,000+ experience of linker compound syntheses, which can provide clients with ADC small molecules ranging from milligrams to kilograms. To date, we have empowered our 600+ customers to develop ADC small molecule projects.

ADC Payload-Linker CDMO Integrated Platform

Payload-Linker Intermediates
  • Preclinical
  • Phase I
  • Phase II
  • Phase III
  • Commercial
Payload-Linker Intermediates
Milligram
Gram
Kilogram
10-100Kg
Payload-Linker Intermediates
  • Quick Response Fast Delivery
  • CMC Services
  • Quality by Design：Continuous Optimization and Improvement
  • Rich Experience Dedicated & Reliable
  • Cost-effective Stable supply

ADC Conjugation Service

  • Linker-Payload Screen
  • Process Development & Optimization
  • Custom Synthesis

Service Type：FFS, FTE, CMC

Non-Specific Conjugation
Cysteine Conjugation (-SH)
Lysine Conjugation (-NH2)
Site-Specific Conjugation
ThioMAb Conjugation
Bridged Cysteine Conjugation

Capacity

Ma’anshan, Anhui Province — ADC &HPAPI Manufacturing

Tofflon separator(OEL＜0.01μg/ m3 ) covering all toxin levels in pharma

SOP Controlled Clean-up: Maximum HPAPI suitability is achieved by negative pressure separators for weighing, process development, handling and pre-lyophilization handling. End-to-end production management in controlled working area.

Kinetic Monitoring: Air dust detection and alarm system, mandatory staff training (SOP for PPE, emergency response).

  • 4,400m2
    GMP KG Scale Plant
  • 4,000L
    Total volume of the reactor