• ADC & High Potency API

    From R&D to Commercial Manufacturing — One Stop Service

    ChemExpress leads the field for ADC drug development providing one-stop CRO & CDMO services for both small molecule and ADC conjugation. Our facilities include R&D laboratories, kilogram-scale GMP plants and commercial-scale GMP manufacturing plants. This enables us to provide end-to-end project support from discovery to commercialization.

    We have a substantial inventory of over 80 payloads and 400 linkers, in addition to extensive experience in linker compound synthesis, with over 1000 successful syntheses. This equips us to deliver ADC small molecules in quantities ranging from milligrams to kilograms. To date, we've supported over 800 clients in developing their ADC projects and completed more than 140 ADC projects.

ADC Payload-Linker CDMO Integrated Platform

Payload-Linker Intermediates
  • Preclinical
  • Phase I
  • Phase II
  • Phase III
  • Commercial
Payload-Linker Intermediates
Milligram
Gram
Kilogram
10-100Kg
Payload-Linker Intermediates
  • Quick Response Fast Delivery
  • CMC Services
  • Quality by Design：Continuous Optimization and Improvement
  • Rich Experience Dedicated & Reliable
  • Cost-effective Stable supply

ADC Conjugation Service

  • Linker-Payload Screen
  • Process Development & Optimization
  • Custom Synthesis

Service Type：FFS, FTE, CMC

Non-Specific Conjugation
Cysteine Conjugation (-SH)
Lysine Conjugation (-NH2)
Site-Specific Conjugation
ThioMAb Conjugation
Bridged Cysteine Conjugation

Capacity

Ma’anshan, Anhui Province — ADC &HPAPI Manufacturing

Tofflon separator(OEL＜0.01μg/ m3 ) covering all toxin levels in pharma

SOP Controlled Clean-up: Maximum HPAPI suitability is achieved by negative pressure separators for weighing, process development, handling and pre-lyophilization handling. End-to-end production management in controlled working area.

Kinetic Monitoring: Air dust detection and alarm system, mandatory staff training (SOP for PPE, emergency response).

  • 4,400m2
    GMP KG Scale Plant
  • 4,000L
    Total volume of the reactor