• Peptide Process Development & Manufacturing

Peptide Integrated Platform

  • ChemExpress specializes in the development and production of peptides, offering custom peptide synthesis, peptide modification, and peptide production services. Our team has extensive experience in solid-phase and liquid-phase chemistry. With scientists having over 10 years of peptide R&D and production experience, we support projects from early discovery to pilot production—milligram to kilogram scale.
    The GMP-grade facility for peptide production, capable of kilogram-scale GMP peptide manufacturing and meeting CMC requirements for peptide-based innovative drugs, will be completed and put into operation by the end of December 2024.
    Online Inquiry

What We Can Offer

Services

  • R&D Platform
    Equipped with multi-channel fully automated peptide synthesizers and automated purification systems, we provide clients with rapid screening, custom peptide synthesis, and peptide modification services in early drug discovery.
  • Development Types
    Peptides, peptide fragments, and peptide-like compounds.
  • Pilot Production Platform
    Supports peptide production from hundreds of grams to kilograms.
  • Analytical Platform
    Equipped with advanced instruments such as UPLC, HPLC, LCMS, UPLC-MS, 2D-LCMS, LCMSMS, QE, GCMSMS, ICPMS, IR, UV, NMR, and XRPD for peptide quality research, method development and validation, structural confirmation, and impurity analysis.

Peptide Types

  • Peptide Synthesis: FTE/FFS/Process Service
    • Linear Peptides: Peptides with no more than 50 amino acids.
    • Cyclic Peptides: Disulfide bond（single cycle, bicycle, tricycle), click reaction, Lactam(single cycle, bicycle), Disulfide bridge in combination with Triazole, stapled peptides.
    • Modified Peptides: N-terminal modifications, C-terminal, modifications, dye/fluorescent labeling, PEGylation, DOTA/NOTA, and isotope labeling.
    • Peptides with Special Amino Acids: Incorporating non-natural or derivative amino acids.
  • Peptide Development and Production
    • Development of peptides (CMC services)
    • Development of PDCs (CMC services)
    • Impurity studies for peptides

Why Partner with ChemExpress

  • Quality
    Standards

    Product purity up to 99%, meeting various requirements

  • Production
    Capacity

    R&D and production from milligram to kilogram scales

  • Technical
    Expertise

    Solid phase peptide
    synthesis and liquid-
    phase synthesis, Fmoc
    method, cyclic peptides,
    and PDCs

  • Extensive
    Experience

    Over 10 years of experience in peptide drug R&D and production.

Equipment

Lab-Scale Equipment
  • Biotage SyroⅡ (36/48 parallel synthesis units)
  • Waters AUTO-P
  • Lyophilizer
Pilot-Scale Equipment
  • Peptide Synthesizers (5L, 20L, 50L, 200L)
  • DAC Systems (DAC100, DAC150, DAC200, DAC300)
  • Lyophilizers (0.5 m², 1 m², 3 m²)

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