Val-Cit-PAB-MMAE
(1)Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a cytotoxic payload MMAE. Monomethyl Auristatin E(MMAE) functions as a potent mitotic inhibitor by inhibiting tubulin polymerization.Valine-citrulline is a common lysosomally cleavable dipeptide. PAB is a typical self-immolative spacer.
We can provide high-quality Val-Cit-PAB-MMAE and its derived impurities.Moreover, we provide the following technical development services:
Reliable and available kilogram-level supply;
kilogram-level GMP supply in commercial production stage;
Complete DMF registration;
CMC and regulatory affair service(IND, NDA) based on this product.
Product Specifications:purity≥99%, Total Impurities≤1.0%, KF≤1.0%
We can provide high-quality Val-Cit-PAB-MMAE and its derived impurities.Moreover, we provide the following technical development services:
Reliable and available kilogram-level supply;
kilogram-level GMP supply in commercial production stage;
Complete DMF registration;
CMC and regulatory affair service(IND, NDA) based on this product.
Product Specifications:purity≥99%, Total Impurities≤1.0%, KF≤1.0%
We can provide high-quality Val-Cit-PAB-MMAE and its derived impurities.
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CAS644981-35-1
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CatalogHY-100374
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Molecular Weight1123.43
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Molecular FormularC58H94N10O12