Services & Solutions
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DiscoveryDiscoveryRead More
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Process DevelopmentProcess DevelopmentRead More
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ManufacturingManufacturingRead More
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ADC & High Potency APIADC & High Potency APIRead More
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Oligonucleotide Process Development & ManufacturingOligonucleotide Process Development & ManufacturingRead More
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Peptide Process Development & ManufacturingPeptide Process Development & ManufacturingRead More
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Analytical Development & Quality ControlAnalytical Development & Quality ControlRead More
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Regulatory CMC SupportRegulatory CMC SupportRead More
Technologies
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High-Throughput Experimentation (HTE)High-Throughput Experimentation (HTE)
ChemExpress has established High-Throughput Experimentation (HTE) platform to keep up with the increasing demand of pharmaceutical timelines in drug discovery and development. HTE is a powerful tool that allows the execution of large numbers of experiments in parallel while requiring limited material and less effort per-experiment. Taking these advantages, we are able to optimize individual steps in a total synthesis for solving complex chemical problems.
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Flow ChemistryFlow Chemistry
ChemExpress has established an industry-leading continuous manufacturing (flow chemistry) platform offering process development and manufacturing services for projects from pre-clinical to commercialization.
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BiocatalysisBiocatalysis
ChemExpress' comprehensive biocatalysis platform provides a one-stop solution for all of your biocatalysis challenges; this includes enzyme screening and fermentation as well as process development and cGMP production.
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Preparative Chromatography ServicePreparative Chromatography Service
ChemExpress offers one-stop preparative chromatographic stand-alone services for separation, purification and production of APIs and advanced intermediates under GMP. We are equipped with prep-HPLC and prep-SFC production systems that can support milligram to kilogram scale production.
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Solid State Chemistry ResearchSolid State Chemistry Research
Our solid-state chemistry research technology platform has served many pharmaceutical companies around the world. It has successfully promoted the process from free form polymorph screening to the scale-up production of commercial ton-scale.
Meanwhile, the Chemexpress platform has close cooperation with well-known pharmaceutical companies concentrating on formulation R&D services, so far, one-stop service has achieved in some varieties from API synthesis process development to commercialization.
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PhotochemistryPhotochemistry
Chemexpresss committed to sustainable development, adhering to the concept of green chemistry, photochemistry can offers a green, cost-effective option.
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Spray Dried DispersionSpray Dried Dispersion
For the active pharmaceutical ingredients (APIs) that fall into BCS (biopharmaceutical classification system) 2 and 4 spaces, advanced formulation approaches are required to enhance their aqueous solubility and bioavailability. Solid amorphous dispersions via spray drying is one of the enabling approaches.
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Hot Melt ExtrusionHot Melt Extrusion
An increasing challenges faced today by the pharmaceutical industry is approximately 40% of currently marketed drugs are classified as poorly soluble (BCS Class II/IV), and more than 70% of drugs in development are also poorly soluble, especially when the molecule has both low solubility and a high dose.
The mechanism of HME is to disperse APIs in the polymer matrix at the molecular level to form amorphous solid dispersions. Amorphous solid dispersions can improve bioavailability in more than 80% of cases. The advantage of HME technology is the capability of continuous manufacturing with solvent-less processing and friendly downstream processing of extrudates into final dosage forms (tablets, capsules, controlled release forms etc). HME is increased use in the pharmaceutical industry.
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Company Profile
One-stop CRO & CDMO Services
Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.
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2006Established
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10+R&D Centers and CDMO Sites
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11,000+Global Partners
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The BIGGEST World ADC meeting uniting 700+ ADC Experts & Enthusiasts Starts Soon!ChemExpress will sponsor the 13th Annual World ADC San Diego 2022. You are welcome to visit us at booth 51 and talk with our scientists and managers.2022.08.31
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ChemExpress has successfully obtained the US FDA DMF filing for Exatecan mesylateChemExpress has successfully obtained the US FDA DMF filing for the API Exatecan mesylate, filing number: MF036708.2022.05.23